Article

EGFL7 promotes immune evasion in glioblastoma by interaction with integrin β <sub>2</sub>

2025-07-31

Abstract excerpt

Glioblastoma is the most aggressive form of malignant brain cancer, characterized by an immunosuppressive microenvironment and immune evasion. Despite the success of immune checkpoint inhibitors in other cancers, immunotherapies such as anti-PD1 have shown limited efficacy in glioblastoma, underscoring the need to identify tumor-intrinsic mechanisms that sustain this immunosuppressive microenvironment and to devel...

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Literature Corpus work: 24a6eb54-f8ae-5684-bf80-a74906b8fc6a
DOI: 10.1101/2025.07.28.667281

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