Article
Cellular senescence in vivo: its relevance in ageing and cardiovascular disease.
Experimental gerontology - 1 Jan 2000
Erusalimsky Jorge D, Kurz David J
Abstract excerpt
In most somatic mammalian cell types extensive replication and various types of cellular insults induce a permanent form of growth arrest called senescence. Senescence has been comprehensively characterised in cell culture, but its occurrence in vivo has only recently started to become appreciated. In this mini-review, we examine the evidence for the occurrence of senescence in vivo, with particular emphasis on...
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