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Cells in Atherosclerosis: Focus on Cellular Senescence from Basic Science to Clinical Practice

5 Dec 2023

Abstract excerpt

Aging is a major risk factor of atherosclerosis through different complex pathways including replicative cellular senescence and age-related clonal hematopoiesis. In addition to aging, extracellular stress factors, such as mechanical and oxidative stress, can induce cellular senescence, defined as premature cellular senescence. Senescent cells can accumulate within atherosclerotic plaques over time and contribute...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 38138958
DOI: 10.3390/ijms242417129

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