Article
[Molecular cloning, expression mutation of myostatin and study on biochemical activity of its C-terminal peptide].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Jul 2003
Yang Xing-Yuan, Hou Jian, An Xiao-Rong, Guan Hong, Gou Ke-Mian, Yang Shu-Hong, Chen Li-Dong, Chen Yong-Fu
Abstract excerpt
Myostatin, a member of the TGF-beta family, negatively regulates skeletal muscle development. Mutation of myostatin activity leads to increases muscle growth and carcass lean yield. The bovine myostatin mutation cDNA was amplified by polymerase chain reaction, and then sub-cloned into the expression vector pET-30a( + ) to form the expression plasmid pET30a (+)-action/ Myostatin. The recombinant plasmid was...
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