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Article

Fhos2, a novel formin‐related actin‐organizing protein, probably associates with the nestin intermediate filament

25 May 2005

Abstract excerpt

Fhos1 is a mammalian formin-family protein, and functions as an organizer of the actin microfilament. Here we have cloned human and mouse cDNAs for a novel Fhos homolog, designated Fhos2. The messages for Fhos2 are expressed in the heart, kidney, and brain, where the Fhos1 mRNAs are not abundant. Two splice variants of Fhos2 exist in a tissue-specific manner; the longer variant Fhos2L is the major form in the...

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PMID: 15966898
DOI: 10.1111/j.1365-2443.2005.00867.x

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