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Article

GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking.

Nature neuroscience - 1 Jul 2005

Hoogenraad Casper C, Milstein Aaron D, Ethell Iryna M, Henkemeyer Mark, Sheng Morgan

Abstract excerpt

The function of the multi-PDZ domain scaffold protein GRIP1 (glutamate receptor interacting protein 1) in neurons is unclear. To explore the function of GRIP1 in hippocampal neurons, we used RNA interference (RNAi) to knock down the expression of GRIP1. Knockdown of GRIP1 by small interfering RNA (siRNA) in cultured hippocampal neurons caused a loss of dendrites, associated with mislocalization of the...

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Source

Identifiers

PMID: 15965473
DOI: 10.1038/nn1487

Genes

GRIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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