Article
Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases.
The Journal of biological chemistry - 12 Aug 2005
Wang Audrey H, Grégoire Serge, Zika Eleni, Xiao Lin, Li Cathy S, Li Hongwei, Wright Kenneth L, Ting Jenny P, Yang Xiang-Jiao
Abstract excerpt
Eighteen human histone deacetylases (HDACs) have been identified, and according to their sequence similarity to yeast homologs, these enzymes are grouped into distinct classes. Within class II, HDAC4, HDAC5, HDAC7, and HDAC9 share similar domain organization both within the N-terminal extension and the C-terminal catalytic domain, thus forming a subclass known as class IIa. These HDACs function as...
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