Article
Cloning and Functional Characterization of HDAC11, a Novel Member of the Human Histone Deacetylase Family
1 Jul 2002
Abstract excerpt
We have cloned and characterized a human cDNA that belongs to the histone deacetylase family, which we designate as HDAC11. The predicted HDAC11 amino acid sequence reveals an open reading frame of 347 residues with a corresponding molecular mass of 39 kDa. Sequence analyses of the putative HDAC11 protein indicate that it contains conserved residues in the catalytic core regions shared by both class I and II...
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