Article
Higher order lipase gene association with plasma triglycerides.
Journal of lipid research - 1 Sept 2005
Reilly Muredach P, Foulkes Andrea S, Wolfe Megan L, Rader Daniel J
Abstract excerpt
Lipoprotein lipase, HL, and endothelial lipase (EL) are proteoglycan-bound enzymes that regulate plasma lipoprotein levels through coordinated triglyceride (TG) lipase and phospholipase activity. We hypothesized that single nucleotide polymorphisms (SNPs) in lipase genes would have higher order impact on plasma lipoproteins beyond the influence of individual SNPs. In a sample of asymptomatic Caucasian subjects (n...
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