Article
Lipoprotein lipase gene variants and the effect of environmental factors on cardiovascular disease risk.
Diabetes, obesity & metabolism - 1 Jan 2004
Talmud Philippa J, Stephens Jeffrey W
Abstract excerpt
Coronary heart disease (CHD) is a major cause of mortality in the Western world. CHD risk is known to be modified by both genetic and environmental factors. In this review, we look at the role of lipoprotein lipase (LPL) gene variants in predisposing to CHD risk and the important interaction between these genotypes and environmental factors (e.g. smoking). Gene-environmental interactions result in a greater than...
Topics
- Coronary Disease
- Genetic Predisposition to Disease
- Humans
- Lipoprotein Lipase
- Risk Factors
- Smoking
