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Article

An underestimated combination of opposites resulting in enhanced thrombotic tendency.

Blood - 1 Oct 2005

Simioni Paolo, Castoldi Elisabetta, Lunghi Barbara, Tormene Daniela, Rosing Jan, Bernardi Francesco

Abstract excerpt

Heterozygous carriers of factor V (FV) Leiden who also carry FV deficiency often develop venous thromboembolism, but the thrombosis risk associated with this rare condition (pseudohomozygous activated protein C resistance) is still unclear. The thrombosis risk of genetically characterized pseudohomozygotes (n = 6) was compared with that of FV Leiden heterozygotes (n = 683) and homozygotes (n = 50) recruited...

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Identifiers

PMID: 15961511
DOI: 10.1182/blood-2005-04-1461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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