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Article

Inactivation of Myc in murine two-hit B lymphomas causes dormancy with elevated levels of interleukin 10 receptor and CD20: implications for adjuvant therapies.

Cancer research - 15 Jun 2005

Yu Duonan, Dews Michael, Park Andrea, Tobias John W, Thomas-Tikhonenko Andrei

Abstract excerpt

Overexpression of c-Myc and inactivation of p53 are hallmarks of human Burkitt's lymphomas. We had previously showed that transduction of murine p53-null bone marrow cells with a Myc-encoding retrovirus is sufficient for B lymphomagenesis. To address the role of Myc in tumor sustenance, we genera...

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Share to Antibodies, Monoclonal, Murine-Derived
Share to Antigens, CD20
Share to Genes, myc

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, B-Cell

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Source

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Identifiers

PMID: 15958595
DOI: 10.1158/0008-5472.CAN-04-4197
PMCID: PMC1490323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15958595-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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