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Article

Mutations in bone marrow-derived stromal stem cells unmask latent malignancy.

Stem cells and development - 1 Aug 2010

Houghton JeanMarie, Li Hanchen, Fan Xueli, Liu Yingwang, Liu Jian Hua, Rao Varada P, Poutahidis Theofilos, Taylor Christie L, Jackson Erin A, Hewes Christine, Lyle Stephen, Cerny Anna, Bowen Glennice, Cerny Jan, Moore Nathan, Kurt-Jones Evelyn A, Erdman Susan E

Abstract excerpt

Neoplastic epithelia may remain dormant and clinically unapparent in human patients for decades. Multiple risk factors including mutations in tumor cells or the stromal cells may affect the switch from dormancy to malignancy. Gene mutations, including p53 mutations, within the stroma of tumors ar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20199238
DOI: 10.1089/scd.2009.0439
PMCID: PMC3135253

Genes

TNF
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20199238-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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