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Controversies in clinical cancer dormancy

11 Jul 2011

Abstract excerpt

Clinical cancer dormancy is defined as an unusually long time between removal of the primary tumor and subsequent relapse in a patient who has been clinically disease-free. The condition is frequently observed in certain carcinomas (e.g., breast cancer), B-cell lymphoma, and melanoma, with relapse occurring 5-25 y later. Clinical data suggest that a majority of breast cancer survivors have cancer cells for...

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PMID: 21746894
DOI: 10.1073/pnas.1106613108

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