Article
Compartmentalized human immunodeficiency virus type 1 present in cerebrospinal fluid is produced by short-lived cells.
Journal of virology - 1 Jul 2005
Harrington Patrick R, Haas David W, Ritola Kimberly, Swanstrom Ronald
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS) during primary infection and persists in this compartment by unknown mechanisms over the course of infection. In this study, we examined viral population dynamics in four asymptomatic subjects commencing antiretroviral therapy to characterize cellular sources of HIV-1 in the CNS. The inability to monitor viruses directly in the...
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