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Article

Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations.

Virology - 1 Mar 2009

Smith Davey M, Zárate Selene, Shao Hai, Pillai Satish K, Letendre Scott L, Wong Joseph K, Richman Douglas D, Frost Simon D W, Ellis Ronald J

Abstract excerpt

INTRODUCTION: We hypothesized that pleocytosis, which is a marker of central nervous system (CNS) inflammation, would result in viral genetic equilibration or de-compartmentalization between HIV populations in the blood and cerebrospinal fluid (CSF), suggesting viral trafficking. METHODS: Study subjects, who started or interrupted their antiretroviral treatment, had viral loads measured and clonal viral env...

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Identifiers

PMID: 19100592
DOI: 10.1016/j.virol.2008.11.010
PMCID: PMC2794037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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