Article
ampC gene expression in promoter mutants of cefoxitin-resistant Escherichia coli clinical isolates.
FEMS microbiology letters - 1 May 2007
Tracz Dobryan M, Boyd David A, Hizon Romeo, Bryce Elizabeth, McGeer Allison, Ofner-Agostini Marianna, Simor Andrew E, Paton Shirley, Mulvey Michael R
Abstract excerpt
Reverse transcriptase polymerase chain reaction was used to determine the amount of overexpression of the ampC gene in 52 cefoxitin-resistant Escherichia coli clinical isolates that had previously characterized mutations in their ampC promoter/attenuator regions. The results showed that mutations that create a consensus -35 box (TTGACA) are the most important factor in strengthening the ampC promoter, followed by...
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