Osteopontin Is Colocalized with the Adhesion Molecule CEACAM1 in the Extravillous Trophoblast of the Human Placenta and Enhances Invasion of CEACAM1-Expressing Placental Cells

Abstract excerpt

CONTEXT: The human placenta is a complex tissue and possesses, through its capacity to proliferate and to invade maternal tissue, qualities that are usually found in malignant tumors. Osteopontin (OPN) and CEACAM1 may regulate these processes. OBJECTIVE: The present study was designed to investigate the expression pattern of OPN in the human placental components and to correlate it with CEACAM1 expression and...

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