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Embryo Implantation and Tumor Metastasis: Common Pathways of Invasion and Angiogenesis

1 Sept 1999

Abstract excerpt

Implantation of the embryo is one of the last great mysteries of reproductive biology. There are striking similarities present between the behavior of invasive placental cells and that of invasive cancer cells. In this review, we propose that cellular mechanisms used by the cells of the placenta during implantation are reused by cancer cells to invade and spread within the body. Integrins and other cell adhesion...

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PMID: 10797946
DOI: 10.1055/s-2007-1016235

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