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Convergent evolution of pregnancy-specific glycoproteins in human and horse

9 Jun 2016

Abstract excerpt

Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy. Until now, PSGs are only found in species that have a highly invasive (hemochorial) placentation including humans, mice and rats. Surprisingly, analyzing the CEACAM gene...

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PMID: 27280409
DOI: 10.1530/rep-16-0236

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Convergent evolution of pregnancy-specific glycoproteins in human and horsePMID 27280409Read ↗

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The Pregnancy-Specific Glycoprotein (PSG) Gene Cluster on Human Chromosome 19: Fine Structure of the 11 PSG Genes and Identification of 6 New Genes Forming a Third Subgroup within the Carcinoembryonic Antigen (CEA) FamilySemantic proximity Read ↗

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