Human trophoblast epithelial-mesenchymal transition in abnormally invasive placenta†

doi:10.1093/biolre/ioy042

Article

Human trophoblast epithelial-mesenchymal transition in abnormally invasive placenta†

9 Feb 2018

Abstract excerpt

Differentiation of first trimester human placental cytotrophoblast (CTB) from an anchorage-dependent epithelial phenotype into the mesenchymal-like invasive extravillous trophoblast (EVT) is crucial in the development of the maternal-fetal interface. We showed previously that differentiation of first trimester CTB to EVT involves an epithelial-mesenchymal transition (EMT). Here we compare the...

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