Article
Polymorphisms of high-affinity IgE receptor and histamine-related genes in patients with ASA-induced urticaria/angioedema.
Journal of Korean medical science - 1 Jun 2005
Choi Jeong-Hee, Kim Seung-Hyun, Suh Chang-Hee, Nahm Dong-Ho, Park Hae Sim
Abstract excerpt
The pathogenic mechanism of ASA-induced urticaria/angioedema (AIU) is still poorly understood, but it has been known that histamine releasing by cutaneous mast cell activation is considered to be an important role. Considering the importance of histamine in AIU, we speculated that a genetic abnormality of histamine-related genes such as a high-affinity IgE receptor, a metabolic enzyme of histamines and histamine...
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