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Article

[Histamine H₁ receptor gene as an allergic diseases-sensitive gene and its impact on therapeutics for allergic diseases].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Feb 2011

Mizuguchi Hiroyuki, Kitamura Yoshiaki, Kondo Yuto, Kuroda Wakana, Yoshida Haruka, Miyamoto Yuko, Hattori Masashi, Takeda Noriaki, Fukui Hiroyuki

Abstract excerpt

Therapeutics targeting disease-sensitive genes are required for the therapy of multifactorial diseases. There is no clinical report on therapeutics for allergic disease-sensitive genes. We are focusing on the histamine H₁ receptor (H1R) as a sensitive gene. H1R mediates allergy histamine signals. H1R is a rate-limiting molecule of the H1R signal because the signal is increased with elevated receptor expression...

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Identifiers

PMID: 21297357
DOI: 10.1248/yakushi.131.171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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