Article
ADAM33: a novel therapeutic target for asthma.
Expert opinion on therapeutic targets - 1 Aug 2003
Powell Robert M, Hamilton Lynnsey M, Holgate Stephen T, Davies Donna E, Holloway John W
Abstract excerpt
The incidence of asthma worldwide is increasing, and the disease has a large unmet clinical need. Despite the availability of anti-inflammatory and bronchodilator medication, there is persisting morbidity and mortality. New approaches are needed to understand the role that structural changes in the airways (remodelling) play in this process. Studies of the genetic basis of asthma have identified the ADAM33 (a...
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