Article
Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes.
The British journal of dermatology - 1 Oct 2006
Chang Y T, Chou C T, Shiao Y M, Lin M W, Yu C W, Chen C C, Huang C H, Lee D D, Liu H N, Wang W J, Tsai S F
Abstract excerpt
BACKGROUND: Besides the HLA-Cw*0602 allele, the psoriasis susceptibility 1 candidate 3 (PSORS1C3) and corneodesmosin (CDSN) genes are two probable psoriasis susceptibility genes in the PSORS1 locus. The -79C, -26C and +246A alleles of the PSORS1C3 gene, the CDSN*971T allele, CDSN*TTC (619T-1236T-1243C) and CDSN*5 (619T-1240G-1243C) are strongly associated with psoriasis in the caucasian population. Until now, no...
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