Article
[Study on the relationship between methylene tetrahydrofolate reductase gene (677C-->T) mutation and skin lesions in endemic arsenic poisoning].
Wei sheng yan jiu = Journal of hygiene research - 1 Mar 2005
Chen Li, Guo Xin-biao, Deng Fu-rong, Liu Hong, Jin Yu, Wang Zhiquan, Zhang Kai
Abstract excerpt
OBJECTIVE: Methylene tetrahydrofolate reductase (MTHFR) is the key enzyme in folate metabolism. We examined whether single nucleotide 677 C-->T mutation in the MTHFR gene could affect the occurrence of skin lesions in endemic arsenic poisoning. METHODS: Fifty individuals with arsenic-induced skin lesions were identified as cases, and 35 individuals without skin lesions from the same village were selected as...
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