Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study.

Clinical chemistry - 1 Aug 2005

Yu Xinhua, Jacobs David R, Schreiner Pamela J, Gross Myron D, Steffes Michael W, Fornage Myriam

Abstract excerpt

BACKGROUND: Uncoupling proteins (UCPs) reduce ATP generation with concomitant increased release of heat. The activities of UCPs have been related to obesity and energy metabolism. METHODS: We investigated the association of the commonly observed UCP2 Ala55Val (V) polymorphism with diabetes mellitus and impaired fasting glucose (IFG) among 3684 participants in the Coronary Artery Risk Development in Young Adults...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black People
Share to Blood Glucose
Share to Fasting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin Resistance

Share to Ion Channels

Share to Membrane Transport Proteins

Share to Mitochondrial Proteins

Share to Uncoupling Protein 2

Source

Identifiers

PMID: 15951317
DOI: 10.1373/clinchem.2004.044859

Genes

UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study.PMID 15951317Read ↗

Uncoupling protein 2 and 3 gene polymorphisms and their association with type 2 diabetes in asian indians.Semantic proximity Read ↗

Association of uncoupling protein-2 -866G/A and Ala55Val polymorphisms with susceptibility to type 2 diabetes mellitus: A meta-analysis of case-control studies.Semantic proximity Read ↗

Ethnicity Differences in the Association of UCP1-3826A/G, UCP2-866G/A and Ala55Val, and UCP3-55C/T Polymorphisms with Type 2 Diabetes Mellitus Susceptibility: An Updated Meta-Analysis.Semantic proximity Read ↗

The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes.Semantic proximity Read ↗

[Common variants in beta 3-adrenergic-receptor and uncoupling protein-2 genes are associated with type 2 diabetes and obesity].Semantic proximity Read ↗

Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM.Semantic proximity Read ↗

The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complicationsSemantic proximity Read ↗

Uncoupling protein 2 -866G/A and uncoupling protein 3 -55C/T polymorphisms in young South African Indian coronary artery disease patients.Semantic proximity Read ↗

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion.Semantic proximity Read ↗

Impact of KCNJ11 rs5219, UCP2 rs659366, and MTHFR rs1801133 Polymorphisms on Type 2 Diabetes: A Cross-Sectional Study.Semantic proximity Read ↗

Uncoupling protein 2 Ala55Val polymorphism is associated with a higher acute insulin response to glucose.Semantic proximity Read ↗

Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.