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Impact of KCNJ11 rs5219, UCP2 rs659366, and MTHFR rs1801133 Polymorphisms on Type 2 Diabetes: A Cross-Sectional Study.

The review of diabetic studies : RDS - 1 Jan 2021

Lapik Irina Alexandrovna, Ranjit Rajesh, Galchenko Alexey Vladimirovich

Abstract excerpt

OBJECTIVE: Type 2 diabetes (T2D) is a multifactorial disease. Its occurrence and prognosis are affected by many genes, including KCNJ11, UCP2, and MTHFR. The objective of this study was to investigate the distribution of various variants of these genes and evaluate their contribution to the outcome of T2D. METHODS: 80 females with T2D and class I-II obesity in the age of 40-65 years old underwent a genetic study,...

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Identifiers

PMID: 34289004
DOI: 10.1900/RDS.2021.17.21
PMCID: PMC9380098

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