Article
[Common variants in beta 3-adrenergic-receptor and uncoupling protein-2 genes are associated with type 2 diabetes and obesity].
Zhonghua yi xue za zhi - 2 Mar 2004
Xiu Ling-ling, Weng Jian-ping, Sui Yi, Wang Jing, Yan Jin-hua, Huang Zhi-min
Abstract excerpt
OBJECTIVE: To investigate the effects of uncoupling protein-2 (UCP2) gene Ala55Val variation and beta(3)-adrenergic-receptor (beta(3)-AR) gene Trp64Arg variation on type 2 diabetes and obesity, as well as the combined effects between the two variations. METHODS: The peripheral blood samples of 173 type 2 diabetics, 119 obese persons, and 177 control subjects were collected. PCR-RFLP was used to detect the UCP2...
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