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Article

Simultaneous detection of two major lamivudine-resistant mutants using competitively differentiated-PCR.

Journal of virological methods - 1 Sept 2005

Peng Xiao Mou, Gu Lin, Huang Yang Su, Ma Hui Hui, Xie Qi Feng, Li Gang, Gao Zhi Liang

Abstract excerpt

Rapid, specific and sensitive methods without advanced equipment are required urgently in developing countries in order to detect or monitor lamivudine-resistant mutants routinely before or in the course of the therapy. A protocol is described for the detection of two major YMDD mutations simultaneously through modifying a previous competitively differentiated-PCR (CD-PCR) by revising the strategy, increasing the...

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Identifiers

PMID: 15950294
DOI: 10.1016/j.jviromet.2005.04.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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