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Article

Rapid and high throughput detection of HBV YMDD mutants with fluorescence polarization.

World journal of gastroenterology - 1 Oct 2003

Bai Yui-Jie, Zhao Jin-Rong, Lv Guan-Ting, Zhang Wen-Hong, Wang Yan, Yan Xiao-Jun

Abstract excerpt

AIM: To develop a simple and rapid detection of HBV gene variants and prediction of lamivudine-resistance in patients. METHODS: Initially, plasmids harboring the wild-type or mutant HBV DNA fragments were used in a model system. The technique was then applied to clinical samples for an analysis of YMDD mutations. The sera were extracted from chronic hepatitis patients who had received lamivudine treatment for...

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Identifiers

PMID: 14562408
DOI: 10.3748/wjg.v9.i10.2344
PMCID: PMC4656493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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