Article
Specific detection of bacillus anthracis using a TaqMan mismatch amplification mutation assay.
BioTechniques - 1 May 2005
Easterday William R, Van Ert Matthew N, Zanecki Shaylan, Keim Paul
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are increasingly recognized as important diagnostic markers for the detection and differentiation of Bacillus anthracis. The use of SNP markers for identifying B. anthracis DNA in environmental samples containing genetically similar bacteria requires the ability to amplify and detect DNA with single nucleotide specificity. We designed a TaqMan mismatch amplification mutation...
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