Article
High resolution genotyping of Bacillus anthracis outbreak strains using four highly mutable single nucleotide repeat markers.
Letters in applied microbiology - 1 May 2008
Kenefic L J, Beaudry J, Trim C, Daly R, Parmar R, Zanecki S, Huynh L, Van Ert M N, Wagner D M, Graham T, Keim P
Abstract excerpt
AIMS: Bacillus anthracis is a genetically monomorphic bacterium with little diversity to be expected during an outbreak. This study used more rapidly evolving genetic markers on outbreak samples to ascertain genetic diversity. METHODS AND RESULTS: Forty-seven isolates from a B. anthracis outbreak during the summer of 2005 in South Dakota were analysed using single nucleotide polymorphisms (SNP) and multi-locus...
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