Article
A multiplex bead-based suspension array assay for interrogation of phylogenetically informative single nucleotide polymorphisms for Bacillus anthracis.
Journal of microbiological methods - 1 Dec 2013
Thierry Simon, Hamidjaja Raditijo A, Girault Guillaume, Löfström Charlotta, Ruuls Robin, Sylviane Derzelle
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are abundant in genomes of all species and represent informative DNA markers extensively used to analyze phylogenetic relationships between strains. Medium to high throughput, open methodologies able to test many SNPs in a minimum time are therefore in great need. By using the versatile Luminex® xTAG technology, we developed an efficient multiplexed SNP genotyping assay to...
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