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Article

Cytocidal effect of Streptococcus pyogenes on mouse neutrophils in vivo and the critical role of streptolysin S.

The Journal of infectious diseases - 1 Jul 2005

Miyoshi-Akiyama Tohru, Takamatsu Daisuke, Koyanagi Madoka, Zhao Jizi, Imanishi Ken'ichi, Uchiyama Takehiko

Abstract excerpt

We analyzed the in vivo dynamics of peritoneal exudate cells (PECs) in mice injected with group A streptococcus (GAS). A live low-virulence strain, as well as heat-killed low- and high-virulence strains, significantly increased the number of PECs (primarily neutrophils), whereas a live high-virulence strain did not. When coinjected with thioglycollate, the live high-virulence strain, as well as most other GAS...

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PMID: 15942900
DOI: 10.1086/430617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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