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Article

An error-prone viral DNA ligase.

Biochemistry - 14 Jun 2005

Lamarche Brandon J, Showalter Alexander K, Tsai Ming-Daw

Abstract excerpt

Our recent demonstration that DNA polymerase X (Pol X), the DNA repair polymerase encoded by the African swine fever virus (ASFV), is extremely error prone during single-nucleotide gap filling led us to hypothesize that it might contribute to genetic variability in ASFV. For the infidelity of Pol X to be relevant, however, the DNA ligase working downstream of it would need to be capable of sealing nicks...

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Identifiers

PMID: 15938630
DOI: 10.1021/bi047706g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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