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Article

NAD+-dependent DNA ligase encoded by a eukaryotic virus.

The Journal of biological chemistry - 28 Sept 2001

Sriskanda V, Moyer R W, Shuman S

Abstract excerpt

We report the production, purification, and characterization of an NAD(+)-dependent DNA ligase encoded by the Amsacta moorei entomopoxvirus (AmEPV), the first example of an NAD(+) ligase from a source other than eubacteria. AmEPV ligase lacks the zinc-binding tetracysteine domain and the BRCT domain that are present in all eubacterial NAD(+) ligases. Nonetheless, the monomeric 532-amino acid AmEPV ligase...

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PMID: 11459847
DOI: 10.1074/jbc.M105643200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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