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Article

Rapid mutation detection in complex genes by heteroduplex analysis with capillary array electrophoresis.

Electrophoresis - 1 Jun 2005

Velasco Eladio, Infante Mar, Durán Mercedes, Esteban-Cardeñosa Eva, Lastra Enrique, García-Girón Carlos, Miner Cristina

Abstract excerpt

Mutational analysis of large multiexon genes without prevalent mutations is a laborious undertaking that requires the use of a high-throughput scanning technique. The Human Genome Project has enabled the development of powerful techniques for mutation detection in large multiexon genes. We have transferred heteroduplex analysis (HA) by conformation-sensitive gel electrophoresis of the two major breast cancer (BC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15937982
DOI: 10.1002/elps.200410425

Genes

MLH1
BRCA1
BRCA2
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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