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Article

Applications of heteroduplex analysis for mutation detection in disease genes.

Human mutation - 1 Jan 1995

Glavac D, Dean M

Abstract excerpt

Double-stranded heteroduplex molecules that form between a mutant and wild-type DNA strand are often distinguished from homoduplex molecules upon gel electrophoresis. This method, heteroduplex analysis (HA), can be performed rapidly without radioisotopes or specialized equipment. Modifications and enhancements of the HA method have been developed that increase the sensitivity of detection of single-base pair...

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Identifiers

PMID: 8680402
DOI: 10.1002/humu.1380060402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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