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Article

Structure-based Design of a Second-generation Lyme Disease Vaccine Based on a C-terminal Fragment of Borrelia burgdorferi OspA

17 May 2005

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15935380
DOI: 10.1016/j.jmb.2005.04.066

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Structure-based Design of a Second-generation Lyme Disease Vaccine Based on a C-terminal Fragment of Borrelia burgdorferi OspAPMID 15935380Read ↗

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A Broadly Conserved Protective Epitope on the Lyme Disease Vaccine Antigen, OspASemantic proximity Read ↗

Single-domain antibodies reveal unique borrelicidal epitopes on the Lyme disease vaccine antigen, outer surface protein A (OspA)Semantic proximity Read ↗

Single-domain antibodies reveal unique borreliacidal epitopes on the Lyme disease vaccine antigen, Outer surface protein A (OspA)Semantic proximity Read ↗

Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions.Semantic proximity Read ↗

Development of novel multi-protein chimeric immunogens that protect against infection with the Lyme disease agent, Borreliella burgdorferiSemantic proximity Read ↗

Development of an OspC-based tetravalent, recombinant, chimeric vaccinogen that elicits bactericidal antibody against diverse Lyme disease spirochete strainsSemantic proximity Read ↗

Structural identification of a key protective B-cell epitope in Lyme disease antigen OspA.Semantic proximity Read ↗

Development of a sequence-based <i>in silico</i> OspA typing method for <i>Borrelia burgdorferi</i> sensu latoSemantic proximity Read ↗

Evaluation of the safety, reactogenicity and immunogenicity of three recombinant outer surface protein (OspA) lyme vaccines in healthy adultsSemantic proximity Read ↗

Comprehensive seroprofiling of sixteen B. burgdorferi OspC: implications for Lyme disease diagnostics design.Semantic proximity Read ↗

Non-pathogenic Borrelia burgdorferi expressing Treponema pallidum TprK and Tp0435 antigens as a novel approach to evaluate syphilis vaccine candidatesSemantic proximity Read ↗

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