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Development of a sequence-based <i>in silico</i> OspA typing method for <i>Borrelia burgdorferi</i> sensu lato

2023-12-01

Abstract excerpt

Lyme disease (LD), caused by spirochete bacteria of the genus Borrelia burgdorferi sensu lato, remains the most common vector-borne disease in the northern hemisphere. Borrelia outer surface protein A (OspA) is an integral surface protein expressed during the tick cycle, and a validated vaccine target. There are at least 20 recognized Borrelia genospecies, that vary in OspA serotype. Traditional serotyping of...

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Literature Corpus work
06f2ddd7-3f5f-56e4-8cc9-6a8a6bd5d7d5
DOI
10.1101/2023.11.30.568280
Open publication

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