Article
No evidence for association between 1858 C/T single-nucleotide polymorphism of PTPN22 gene and primary Sjögren's syndrome.
Genes and immunity - 1 Aug 2005
Ittah M, Gottenberg J-E, Proust A, Hachulla E, Puechal X, Loiseau P, Mariette X, Miceli-Richard C
Abstract excerpt
One-third of first-degree relatives of patients with primary Sjögren's syndrome (pSS) suffer from other autoimmune diseases, including type I diabetes, systemic lupus erythematosus and autoimmune thyroiditis. Recently, 1858 C/T polymorphism of PTPN22 gene was reported to predispose to these autoimmune diseases. We decided to investigate whether PTPN22 gene polymorphism was also involved in the genetic...
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