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Article

C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition.

Human immunology - 1 Jul 2005

Rueda Blanca, Núñez Concepción, Orozco Gisela, López-Nevot M Angel, de la Concha Emilio G, Martin Javier, Urcelay Elena

Abstract excerpt

Recent findings have demonstrated that the single nucleotide polymorphism 1858C-->T located at the P1 motif of the PTPN22 (protein tyrosine phosphatase nonreceptor 22) gene has functional relevance and is associated with a variety of autoimmune diseases. The aim of this study was to assess the role of the PTPN22 1858C-->T polymorphism in the genetic predisposition to celiac disease (CD). We analyzed a...

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Source

Identifiers

PMID: 16112033
DOI: 10.1016/j.humimm.2005.04.008

Genes

PTPN22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition.PMID 16112033Read ↗

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Protein tyrosine phosphatase non-receptor type 22 gene variants at position 1858 are associated with type 1 and type 2 diabetes in Estonian population.Semantic proximity Read ↗

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Role of the C1858T polymorphism of protein tyrosine phosphatase non-receptor type 22 (PTPN22) in children and adolescents with type 1 diabetes.Semantic proximity Read ↗

The functional R620W variant of the PTPN22 gene is associated with celiac disease.Semantic proximity Read ↗

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