Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotyping Parkinson disease-associated mitochondrial polymorphisms.

Clinical medicine & research - 1 May 2004

Jiang Yiguo, Ellis Tammy, Greenlee Anne R

Abstract excerpt

OBJECTIVE: The purpose of this study was to establish a system for rapidly detecting single nucleotide polymorphisms (SNPs) in mitochondrial DNA (mtDNA) using hybridization probes and melting temperature (T(m)) analysis. This technology should prove useful for population-based studies on the interaction between genetic factors and environmental exposures and the risk of Parkinson disease (PD). METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to DNA, Mitochondrial
Share to DNA Primers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Nucleic Acid Hybridization

Share to Parkinson Disease

Share to Polymorphism, Single Nucleotide

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 15931342
DOI: 10.3121/cmr.2.2.99
PMCID: PMC1069078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotyping Parkinson disease-associated mitochondrial polymorphisms.PMID 15931342Read ↗

A mitochondrial blood-based patient stratification candidate biomarker for Parkinson’s diseaseSemantic proximity Read ↗

High-Resolution Melting Analysis as a Developed Method for Genotyping the PD Susceptibility Loci in LRRK2 Gene.Semantic proximity Read ↗

Mitochondrial DNA screening by melting curve analysis using peptide nucleic acid probes.Semantic proximity Read ↗

A blood-based marker of mitochondrial DNA damage in Parkinson’s diseaseSemantic proximity Read ↗

A simultaneous LightCycler detection assay for five genetic polymorphisms influencing drug sensitivity.Semantic proximity Read ↗

Melting curve analysis of SNPs (McSNP): a gel-free and inexpensive approach for SNP genotyping.Semantic proximity Read ↗

Genotyping of single-nucleotide polymorphisms by high-resolution melting of small amplicons.Semantic proximity Read ↗

DNA melting analysis for detection of single nucleotide polymorphisms.Semantic proximity Read ↗

Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease.Semantic proximity Read ↗

Mitochondrial D-Loop Region Methylation and Copy Number in Peripheral Blood DNA of Parkinson’s Disease PatientsSemantic proximity Read ↗

Single probe PCR melting curve analysis MTHFR C677T SNP sites.Semantic proximity Read ↗

Detection of common disease-causing mutations in mitochondrial DNA (mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes MTTL1 3243 A>G and myoclonic epilepsy associated with ragged-red fibers MTTK 8344A>G) by real-time polymerase chain reaction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.