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Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease.

Human genetics - 1 Feb 2004

Wu Yih-Ru, Wang Cheng-Kuang, Chen Chiung-Mei, Hsu Yuying, Lin Sih-Jing, Lin Yi-Ying, Fung Hon-Chung, Chang Kuo-Hsuan, Lee-Chen Guey-Jen

Abstract excerpt

Parkinson's disease (PD) involves several genetic and environmental components. Heat-shock protein 70, a chaperone that is up-regulated in stress responses and that refolds protein, may be involved in the pathogenesis of PD. We have investigated the association of polymorphisms -110 A/C, +190 G/C, +1267 A/G, +2074 G/C, and +2437 G/C in the 5' and coding regions of the HSP70-1, HSP70-2, and HSP70-hom genes with...

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PMID: 14605873
DOI: 10.1007/s00439-003-1050-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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