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Article

Empirical codon substitution matrix.

BMC bioinformatics - 1 Jun 2005

Schneider Adrian, Cannarozzi Gina M, Gonnet Gaston H

Abstract excerpt

BACKGROUND: Codon substitution probabilities are used in many types of molecular evolution studies such as determining Ka/Ks ratios, creating ancestral DNA sequences or aligning coding DNA. Until the recent dramatic increase in genomic data enabled construction of empirical matrices, researchers relied on parameterized models of codon evolution. Here we present the first empirical codon substitution matrix...

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Identifiers

PMID: 15927081
DOI: 10.1186/1471-2105-6-134
PMCID: PMC1173088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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