Article
Activation of Rac1 or Cdc42 during early morphogenesis of eye discs induces ectopic antennae in Drosophila.
Development, growth & differentiation - 1 May 2005
Go Masahiro J
Abstract excerpt
The Rho family small guanosine triphosphatases (GTPases) play important roles in many cellular processes, especially in regulation of cytoskeletal organization. In this study, I examined the functions of Rac1 and Cdc42 for disc morphogenesis in Drosophila. I expressed either a constitutively active form or a dominant negative form of each protein during early morphogenesis of eye discs. Inactivation of Rac1 or...
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