Article
Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein.
Cell - 29 May 1992
Usheva A, Maldonado E, Goldring A, Lu H, Houbavi C, Reinberg D, Aloni Y
Abstract excerpt
Fractionation of a transcription-competent HeLa cell extract on a column containing one copy of the heptamer repeat (YSPTSPS) present in the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II resulted in the loss of transcriptional activity. Fractionation of the extracts on columns containing mutations of the heptamer repeat was without effect. Such transcriptionally inactive extracts...
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