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Article

Endoplasmic reticulum-associated protein quality control and degradation: genome-wide screen for ERAD components.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005

Schäfer Antje, Wolf Dieter H

Abstract excerpt

In this chapter, a genetic approach is presented that leads to the isolation of mutants and to the identification of proteins involved in protein quality control and endoplasmic reticulum-associated degradation (ERAD). The method makes use of a genomic screen of a yeast deletion library (EUROSCARF). Transformation of each of the approx 5000 strains deleted in one nonvital gene each with a CPY* chimera containing...

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PMID: 15917640
DOI: 10.1385/1-59259-895-1:289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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