Article
Yeast as a Heterologous Model System to Uncover Type III Effector Function.
PLoS pathogens - 1 Feb 2016
Popa Crina, Coll Núria S, Valls Marc, Sessa Guido
Abstract excerpt
Type III effectors (T3E) are key virulence proteins that are injected by bacterial pathogens inside the cells of their host to subvert cellular processes and contribute to disease. The budding yeast Saccharomyces cerevisiae represents an important heterologous system for the functional characterisation of T3E proteins in a eukaryotic environment. Importantly, yeast contains eukaryotic processes with low...
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